Respiratory · UKMLA & AKT
Occupational lung disease (pneumoconioses)
A free high-yield preview for the UKMLA Applied Knowledge Test, covering how to recognise this condition. The full SA Note notes add investigations, management and complications, with practice questions on this topic.
Key high-yield points
- Upper lobes are better ventilated than perfused (V/Q >1) so inhaled particles deposit there - explains upper zone predominance in inhalation diseases. Lower lobes are better perfused (V/Q <1) - explains lower zone predominance in systemic/drug/connective tissue disease.
CHARTS = upper zone fibrosis causes: Coal workers' pneumoconiosis, Histiocytosis/Hypersensitivity pneumonitis, Ankylosing spondylitis/ABPA, Radiation, Tuberculosis, Silicosis/Sarcoidosis. ACID = lower zone fibrosis causes: Asbestosis, Connective tissue disease, Idiopathic pulmonary fibrosis, Drugs (methotrexate, nitrofurantoin, amiodarone).
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