General practice & prim · UKMLA & AKT
Opioid use disorder
A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise opioid use disorder — the full SA Note notes add investigations, management, complications and 10 practice questions.
Key high-yield points
- Opioids bind mu (μ) receptors - analgesia, euphoria, sedation, miosis, respiratory depression
- Chronic use upregulates noradrenergic tone; withdrawal = rebound sympathetic surge (tachycardia, hypertension, sweating, diarrhoea)
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