Dermatology · UKMLA & AKT

Skin manifestations of liver disease

A free high-yield preview for the UKMLA Applied Knowledge Test, covering how to recognise this condition. The full SA Note notes add investigations, management and complications, with practice questions on this topic.

Key high-yield points

  • Skin signs of liver disease arise through four mechanisms: bilirubin accumulation, oestrogen excess, portal hypertension, and synthetic failure (clotting factors, albumin).

Spider naevi and palmar erythema can be normal in pregnancy. When found together in a non-pregnant adult, particularly with other signs, they strongly warrant liver function testing.

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