Dermatology · UKMLA & AKT

Skin manifestations of liver disease

A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise skin manifestations of liver disease — the full SA Note notes add investigations, management, complications and 10 practice questions.

Key high-yield points

  • Skin signs of liver disease arise through four mechanisms: bilirubin accumulation, oestrogen excess, portal hypertension, and synthetic failure (clotting factors, albumin).

Spider naevi and palmar erythema can be normal in pregnancy. When found together in a non-pregnant adult, particularly with other signs, they strongly warrant liver function testing.

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