Acute & emergency · UKMLA & AKT
Acute haemolytic transfusion reaction
A free high-yield preview for the UKMLA Applied Knowledge Test, covering how to recognise this condition. The full SA Note notes add investigations, management and complications, with practice questions on this topic.
Key high-yield points
- Caused by ABO-incompatible blood - almost always human error (mislabelled sample, failed identity check)
- Preformed IgM anti-ABO antibodies → classical complement activation → intravascular haemolysis + macrophage cytokine release → fever, pain, shock
Unlock the full Acute haemolytic transfusion reaction revision
Get the complete high-yield notes (4 more sections covering investigations, management and complications), practice questions, mock exams and Sal, the AI tutor. Start free.