Child health · UKMLA & AKT

Anaphylaxis

A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise anaphylaxis — the full SA Note notes add investigations, management, complications and 10 practice questions.

Key high-yield points

  • Sudden onset, rapidly progressive reaction with airway and/or breathing and/or circulation compromise, usually with skin/mucosal changes. Absence of skin changes does not exclude the diagnosis.
  • Urticaria/erythema - pruritic wheals; present in up to 80%
  • Angioedema - swelling of lips, tongue, face, throat
  • Stridor - laryngeal oedema, upper airway obstruction; greater immediate threat to life than bronchoconstriction
  • Wheeze/dyspnoea - lower airway bronchoconstriction
  • Hypotension and tachycardia - distributive shock; SBP <90 mmHg is a red flag

Stridor = laryngeal oedema = upper airway obstruction. This takes absolute priority - nebulised bronchodilators do NOT address upper airway oedema and must never delay IM adrenaline.

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