Child health · UKMLA & AKT

Diabetes mellitus type 2

A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise diabetes mellitus type 2 — the full SA Note notes add investigations, management, complications and 10 practice questions.

Key high-yield points

  • Rising incidence driven by obesity epidemic; peaks during puberty (physiological insulin resistance from growth hormone surges)
  • Disproportionately affects South Asian, Black African-Caribbean, and East Asian children
  • Mechanism: insulin resistance → compensatory hyperinsulinaemia → beta cell exhaustion → relative insulin deficiency (no autoimmune destruction)

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