Acute & emergency · UKMLA & AKT

Beta-blocker and calcium channel blocker overdose

A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise beta-blocker and calcium channel blocker overdose — the full SA Note notes add investigations, management, complications and 10 practice questions.

Key high-yield points

  • Beta-blockers and calcium channel blockers (CCBs) are among the most dangerous cardiac drugs in overdose - both depress conduction and contractility, causing life-threatening bradycardia and cardiogenic shock. Modified-release preparations delay onset by 6-12 hours.

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