Surgery · UKMLA & AKT

Breast cancer

A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise breast cancer — the full SA Note notes add investigations, management, complications and 10 practice questions.

Key high-yield points

  • Most common cancer in the UK - ~55,000 new diagnoses/year; affects ~1 in 7 women
  • 80% of cases in women over 50; second most common cause of cancer death in women
  • 5-10% hereditary - most commonly BRCA1 (chromosome 17q) or BRCA2 (chromosome 13q) mutations; BRCA1 lifetime risk ~65-85%

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