Child health · UKMLA & AKT
Diabetes mellitus type 1
A free high-yield preview for the UKMLA Applied Knowledge Test, covering how to recognise this condition. The full SA Note notes add investigations, management and complications, with practice questions on this topic.
Key high-yield points
- T1DM - autoimmune T-cell mediated destruction of pancreatic beta cells → absolute insulin deficiency → hyperglycaemia
- Most common form of diabetes in childhood - accounts for >90% of diabetes in under-25s
- ~29,000 children and young people affected in the UK; incidence rising, especially in under-5s
- 3x more likely if father affected than mother; positive family history in 12-15% of under-15s
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