Clinical haematology · UKMLA & AKT
Haemophilia A and B
A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise haemophilia a and b — the full SA Note notes add investigations, management, complications and 10 practice questions.
Key high-yield points
- Haemophilia A - factor VIII deficiency; ~1 in 5,000 male births; accounts for ~80% of cases
- Haemophilia B (Christmas disease) - factor IX deficiency; ~1 in 25,000 male births
- Inheritance - X-linked recessive; affects males almost exclusively; ~1/3 of cases are de novo mutations (negative family history does not exclude diagnosis)
Unlock the full Haemophilia A and B revision
Get the complete high-yield notes (6 more sections covering investigations, management and complications), 10 practice questions, mock exams and AI tutoring. Start free.