Child health · UKMLA & AKT

Kawasaki disease

A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise kawasaki disease — the full SA Note notes add investigations, management, complications and 10 practice questions.

Key high-yield points

  • Medium-vessel vasculitis predominantly affecting children under 5. Diagnosis requires fever ≥5 days plus at least 4 of 5 CREAM features.
  • Conjunctivitis - bilateral, non-exudative (no discharge)
  • Rash - polymorphous (maculopapular/urticarial), widespread; never vesicular
  • Erythema/oedema of hands and feet - progresses to periungual desquamation in subacute phase
  • Adenopathy - unilateral cervical lymphadenopathy, nodes typically >1.5 cm
  • Mucosal changes - dry cracked lips, strawberry tongue

Child appears disproportionately unwell and irritable - more toxic than expected for a viral illness. Fever is typically unresponsive to antipyretics.

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