Infection · UKMLA & AKT
Leptospirosis (Weil's disease)
A free high-yield preview for the UKMLA Applied Knowledge Test, covering how to recognise this condition. The full SA Note notes add investigations, management and complications, with practice questions on this topic.
Key high-yield points
- Systemic zoonotic infection caused by the spirochaete Leptospira interrogans; severe form = Weil's disease (jaundice + AKI), mortality 10-15%
- Transmission - penetration of skin/mucous membranes via contaminated fresh water or soil (rat urine); NOT spread person-to-person
- High-risk groups - farmers, sewer workers, water sports participants (canoeing, triathlon, open-water swimming), returning travellers from tropics
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