Infection · UKMLA & AKT
Leptospirosis (Weil's disease)
A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise leptospirosis (weil's disease) — the full SA Note notes add investigations, management, complications and 10 practice questions.
Key high-yield points
- Systemic zoonotic infection caused by the spirochaete Leptospira interrogans; severe form = Weil's disease (jaundice + AKI), mortality 10-15%
- Transmission - penetration of skin/mucous membranes via contaminated fresh water or soil (rat urine); NOT spread person-to-person
- High-risk groups - farmers, sewer workers, water sports participants (canoeing, triathlon, open-water swimming), returning travellers from tropics
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