Gastroenterology · UKMLA & AKT
Lynch syndrome (HNPCC)
A free high-yield preview for the UKMLA Applied Knowledge Test, covering how to recognise this condition. The full SA Note notes add investigations, management and complications, with practice questions on this topic.
Key high-yield points
- Lynch syndrome (HNPCC) is the most common hereditary colorectal cancer syndrome, caused by germline mutations in DNA mismatch repair (MMR) genes, accounting for 3-5% of all colorectal cancers.
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