Cardiovascular · UKMLA & AKT
Mitral valve prolapse
A free high-yield preview for the UKMLA Applied Knowledge Test, covering how to recognise this condition. The full SA Note notes add investigations, management and complications, with practice questions on this topic.
Key high-yield points
- MVP is the most common extra-renal cardiac complication of ADPKD (~25% of patients)
- Marfan syndrome - fibrillin-1 mutation; MVP in up to 75%
- Ehlers-Danlos syndrome - defective collagen synthesis
- Turner syndrome (45,X)
- Congenital heart disease (ASD, PDA), Wolff-Parkinson-White, long-QT syndrome
In an ADPKD vignette asking about cardiac complications, MVP is the answer - not intracranial aneurysm (vascular, not cardiac) and not Chiari malformation.
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