Cardiovascular · UKMLA & AKT
Mitral valve prolapse
A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise mitral valve prolapse — the full SA Note notes add investigations, management, complications and 10 practice questions.
Key high-yield points
- MVP is the most common extra-renal cardiac complication of ADPKD (~25% of patients)
- Marfan syndrome - fibrillin-1 mutation; MVP in up to 75%
- Ehlers-Danlos syndrome - defective collagen synthesis
- Turner syndrome (45,X)
- Congenital heart disease (ASD, PDA), Wolff-Parkinson-White, long-QT syndrome
In an ADPKD vignette asking about cardiac complications, MVP is the answer - not intracranial aneurysm (vascular, not cardiac) and not Chiari malformation.
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