Neurology · UKMLA & AKT
Myasthenia gravis
A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise myasthenia gravis — the full SA Note notes add investigations, management, complications and 10 practice questions.
Key high-yield points
- Fatigable weakness - worsens with repeated activity, recovers with rest; worse toward end of day
- Ptosis - drooping of one or both eyelids; often first symptom
- Diplopia - extraocular muscle weakness, fatigable on sustained upgaze
- Dysphagia - difficulty swallowing; aspiration risk
- Proximal limb weakness - difficulty climbing stairs, rising from a chair, raising arms
- Reflexes preserved - key differentiator from GBS (areflexia); sensation entirely intact; no UMN signs
MG causes fatigable weakness with preserved reflexes and no sensory disturbance. GBS causes areflexia with sensory involvement. Never confuse the two.
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