Endocrine & metabolic · UKMLA & AKT

Secondary hypertension

A free high-yield preview for the UKMLA Applied Knowledge Test, covering how to recognise this condition. The full SA Note notes add investigations, management and complications, with practice questions on this topic.

Key high-yield points

  • Secondary hypertension = ~10% of all hypertension; remaining 90% is essential (primary)
  • Suspect secondary cause in: young patients, resistant hypertension (BP above target despite 3 agents at optimal doses, one a diuretic), biochemical abnormalities (especially hypokalaemia), no family history

Primary hyperaldosteronism is the most common secondary cause of hypertension in hypertensive clinic populations (~5-10%). Always consider it in young patients with resistant hypertension - even with normal potassium.

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