Endocrine & metabolic · UKMLA & AKT

Primary hyperaldosteronism (Conn's syndrome)

A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise primary hyperaldosteronism (conn's syndrome) — the full SA Note notes add investigations, management, complications and 10 practice questions.

Key high-yield points

  • Most common endocrine cause of secondary hypertension and most common surgically correctable cause of high BP
  • Autonomous, renin-independent overproduction of aldosterone from the adrenal cortex
  • Accounts for ~5-10% of all hypertension; 10-20% of resistant hypertension

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