Acute & emergency · UKMLA & AKT

Sepsis

A free high-yield preview for the UKMLA Applied Knowledge Test, covering how to recognise this condition. The full SA Note notes add investigations, management and complications, with practice questions on this topic.

Key high-yield points

  • Sepsis = dysregulated host response to infection causing organ dysfunction - not simply 'severe infection'
  • qSOFA (bedside screening, score ≥2 triggers urgent assessment): altered mentation + RR ≥22 + SBP ≤100 mmHg
  • Septic shock = sepsis + vasopressor-dependent hypotension + lactate >2 mmol/L despite resuscitation

A temperature persistently elevated despite antipyretics suggests bacterial rather than viral infection - do not be falsely reassured by a 'minor' source.

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