Acute & emergency · UKMLA & AKT
Sepsis
A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise sepsis — the full SA Note notes add investigations, management, complications and 10 practice questions.
Key high-yield points
- Sepsis = dysregulated host response to infection causing organ dysfunction - not simply 'severe infection'
- qSOFA (bedside screening, score ≥2 triggers urgent assessment): altered mentation + RR ≥22 + SBP ≤100 mmHg
- Septic shock = sepsis + vasopressor-dependent hypotension + lactate >2 mmol/L despite resuscitation
A temperature persistently elevated despite antipyretics suggests bacterial rather than viral infection - do not be falsely reassured by a 'minor' source.
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