Child health · UKMLA & AKT

Whooping cough (pertussis)

A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise whooping cough (pertussis) — the full SA Note notes add investigations, management, complications and 10 practice questions.

Key high-yield points

  • Caused by Bordetella pertussis - Gram-negative coccobacillus; spread by respiratory droplets
  • Pertussis toxin prevents lymphocyte trafficking → lymphocytosis (classic FBC finding); tracheal cytotoxin destroys ciliated cells → impaired mucus clearance → paroxysmal coughing → inspiratory whoop

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