Respiratory · UKMLA & AKT
Asbestos-related pleural disease
A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise asbestos-related pleural disease — the full SA Note notes add investigations, management, complications and 10 practice questions.
Key high-yield points
- Four distinct conditions: pleural plaques, diffuse pleural thickening, benign asbestos pleural effusion, malignant mesothelioma - can coexist
- Latency of 20-40 years from first exposure to presentation
- Typical patient: man >60, occupational history in shipbuilding, construction, insulation (1960s-70s); also ask about para-occupational exposure (e.g. spouse's contaminated workwear)
- Amphibole fibres (crocidolite - blue asbestos) most carcinogenic; serpentine chrysotile (white) least
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