Clinical haematology · UKMLA & AKT
Burkitt lymphoma
A free high-yield preview for the UKMLA Applied Knowledge Test, covering how to recognise this condition. The full SA Note notes add investigations, management and complications, with practice questions on this topic.
Key high-yield points
- Highly aggressive mature B-cell non-Hodgkin lymphoma - fastest doubling time (~24-48 hours) of any human malignancy
- Defined by translocation of c-MYC oncogene (chromosome 8) to an immunoglobulin gene locus
- Despite aggressive biology, potentially curable with intensive chemotherapy
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