Clinical haematology · UKMLA & AKT
Burkitt lymphoma
A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise burkitt lymphoma — the full SA Note notes add investigations, management, complications and 10 practice questions.
Key high-yield points
- Highly aggressive mature B-cell non-Hodgkin lymphoma - fastest doubling time (~24-48 hours) of any human malignancy
- Defined by translocation of c-MYC oncogene (chromosome 8) to an immunoglobulin gene locus
- Despite aggressive biology, potentially curable with intensive chemotherapy
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