Cardiovascular · UKMLA & AKT
Cardiogenic shock
A free high-yield preview for the UKMLA Applied Knowledge Test, covering how to recognise this condition. The full SA Note notes add investigations, management and complications, with practice questions on this topic.
Key high-yield points
- Heart fails to generate sufficient cardiac output to meet metabolic demands - 40-50% 30-day mortality
- Haemodynamic signature: low CO, cardiac index <2.2 L/min/m², high SVR, high PCWP (>18 mmHg), SBP <90 mmHg persisting >30 minutes
- Mechanism: reduced contractility → low CO → baroreceptor-mediated vasoconstriction (↑SVR) → worsens pump function (vicious cycle); back-pressure → pulmonary oedema
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