Cardiovascular · UKMLA & AKT

Distributive shock (septic shock)

A free high-yield preview for the UKMLA Applied Knowledge Test, covering how to recognise this condition. The full SA Note notes add investigations, management and complications, with practice questions on this topic.

Key high-yield points

  • Septic shock = sepsis with circulatory, cellular, and metabolic abnormalities severe enough to substantially increase mortality. All three criteria must be present (Sepsis-3):
  • Confirmed or suspected infection
  • Vasopressor requirement to maintain MAP ≥65 mmHg
  • Serum lactate >2 mmol/L despite adequate fluid resuscitation

This combination carries >40% hospital mortality.

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