General practice & prim · UKMLA & AKT

Chronic fatigue syndrome

A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise chronic fatigue syndrome — the full SA Note notes add investigations, management, complications and 10 practice questions.

Key high-yield points

  • ME/CFS is a neuroimmune condition characterised by profound fatigue not explained by other causes, significantly worsened by exertion. NICE 2021 (NG206) removed graded exercise therapy and repositioned CBT.

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