Acute & emergency · UKMLA & AKT
Colonic perforation
A free high-yield preview for the UKMLA Applied Knowledge Test, covering how to recognise this condition. The full SA Note notes add investigations, management and complications, with practice questions on this topic.
Key high-yield points
- Decreased mesenteric blood flow → mucosal ischaemia → transmural necrosis → perforation
- Causes: atherosclerosis, thrombosis, or embolism (e.g. from atrial fibrillation)
- Splenic flexure and sigmoid colon most vulnerable - watershed blood supply between SMA and IMA territories
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