Acute & emergency · UKMLA & AKT
Colonic perforation
A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise colonic perforation — the full SA Note notes add investigations, management, complications and 10 practice questions.
Key high-yield points
- Decreased mesenteric blood flow → mucosal ischaemia → transmural necrosis → perforation
- Causes: atherosclerosis, thrombosis, or embolism (e.g. from atrial fibrillation)
- Splenic flexure and sigmoid colon most vulnerable - watershed blood supply between SMA and IMA territories
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