Acute & emergency · UKMLA & AKT

Perforated peptic ulcer

A free high-yield preview for the UKMLA Applied Knowledge Test, covering how to recognise this condition. The full SA Note notes add investigations, management and complications, with practice questions on this topic.

Key high-yield points

  • A surgical emergency where a peptic ulcer erodes through all layers of the gastric or duodenal wall, releasing contents into the peritoneum - causing chemical then bacterial peritonitis. Duodenal ulcers are the most common site. Mortality 10-40%, rising sharply with delay to surgery.

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