Cancer · UKMLA & AKT
Diffuse large B-cell lymphoma (DLBCL)
A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise diffuse large b-cell lymphoma (dlbcl) — the full SA Note notes add investigations, management, complications and 10 practice questions.
Key high-yield points
- Most common non-Hodgkin lymphoma subtype - 30-35% of all NHL
- Peak incidence sixth and seventh decades; slightly more common in men
- Aggressive but potentially curable - 60-70% achieve long-term remission with R-CHOP
- Richter transformation - CLL transforming into DLBCL; suspect if known CLL patient develops sudden dramatic lymph node enlargement + B-symptoms
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