Cancer · UKMLA & AKT
Diffuse large B-cell lymphoma (DLBCL)
A free high-yield preview for the UKMLA Applied Knowledge Test, covering how to recognise this condition. The full SA Note notes add investigations, management and complications, with practice questions on this topic.
Key high-yield points
- Most common non-Hodgkin lymphoma subtype - 30-35% of all NHL
- Peak incidence sixth and seventh decades; slightly more common in men
- Aggressive but potentially curable - 60-70% achieve long-term remission with R-CHOP
- Richter transformation - CLL transforming into DLBCL; suspect if known CLL patient develops sudden dramatic lymph node enlargement + B-symptoms
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