Musculoskeletal · UKMLA & AKT
Fibromyalgia
A free high-yield preview for the UKMLA Applied Knowledge Test, covering how to recognise this condition. The full SA Note notes add investigations, management and complications, with practice questions on this topic.
Key high-yield points
- Chronic centralised pain disorder - widespread musculoskeletal pain, fatigue, and cognitive difficulties with NO identifiable inflammatory or structural pathology
- Mechanism: central sensitisation - heightened CNS excitability causing allodynia and hyperalgesia; disorder of pain processing, not primary muscle/joint disease
- Women ~10x more affected; typical age 20-50 years
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