Endocrine & metabolic · UKMLA & AKT
Graves disease (including thyroid eye disease)
A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise graves disease (including thyroid eye disease) — the full SA Note notes add investigations, management, complications and 10 practice questions.
Key high-yield points
- Hyperthyroidism features: weight loss, heat intolerance, sweating, palpitations/tachycardia, anxiety, tremor, diarrhoea, proximal myopathy
- Diffuse smooth goitre - may have audible bruit
- Extrathyroidal features unique to Graves (not other causes of hyperthyroidism):
- Exophthalmos/proptosis - most specific distinguishing feature from other causes
- Pretibial myxoedema - non-pitting indurated plaques over shins
- Thyroid acropachy - rare but pathognomonic
Exophthalmos is the single feature most strongly distinguishing Graves from all other causes of hyperthyroidism. Goitre and anti-TPO antibodies are non-specific (both occur in Hashimoto's).
Unlock the full Graves disease (including thyroid eye disease) revision
Get the complete high-yield notes (4 more sections covering investigations, management and complications), 10 practice questions, mock exams and AI tutoring. Start free.