Endocrine & metabolic · UKMLA & AKT
Hyperprolactinaemia
A free high-yield preview for the UKMLA Applied Knowledge Test, covering how to recognise this condition. The full SA Note notes add investigations, management and complications, with practice questions on this topic.
Key high-yield points
- Dopamine tonically inhibits prolactin via D2 receptors on lactotrophs - anything that blocks this dopaminergic brake raises prolactin
- Raised prolactin → suppressed GnRH → suppressed LH/FSH → hypogonadism (amenorrhoea, reduced libido, erectile dysfunction) + galactorrhoea
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