Endocrine & metabolic · UKMLA & AKT
Hyperprolactinaemia
A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise hyperprolactinaemia — the full SA Note notes add investigations, management, complications and 10 practice questions.
Key high-yield points
- Dopamine tonically inhibits prolactin via D2 receptors on lactotrophs - anything that blocks this dopaminergic brake raises prolactin
- Raised prolactin → suppressed GnRH → suppressed LH/FSH → hypogonadism (amenorrhoea, reduced libido, erectile dysfunction) + galactorrhoea
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