Child health · UKMLA & AKT

Hyposplenism/splenectomy

A free high-yield preview for the UKMLA Applied Knowledge Test, covering how to recognise this condition. The full SA Note notes add investigations, management and complications, with practice questions on this topic.

Key high-yield points

  • Hyposplenism arises from surgical removal or functional loss (e.g. autosplenectomy in sickle cell disease). The core risk is overwhelming post-splenectomy infection (OPSI) with encapsulated organisms - preventable with vaccination and antibiotic prophylaxis.

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