Child health · UKMLA & AKT

Invasive candidiasis in children

A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise invasive candidiasis in children — the full SA Note notes add investigations, management, complications and 10 practice questions.

Key high-yield points

  • Invasive candidiasis = haematogenous spread with end-organ seeding; most common invasive fungal infection in hospitalised children
  • Neonates <28 weeks or <1 kg carry highest risk (incidence 2-5% in very low birthweight infants)
  • Candida albicans most common species overall; non-albicans species (C. parapsilosis, C. glabrata, C. tropicalis) increasingly important - C. glabrata commonly fluconazole-resistant, C. krusei intrinsically resistant

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