Gastroenterology · UKMLA & AKT
Lactose intolerance
A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise lactose intolerance — the full SA Note notes add investigations, management, complications and 10 practice questions.
Key high-yield points
- Insufficient brush-border lactase → unabsorbed lactose in colon → osmotic diarrhoea (water drawn into lumen) + bacterial fermentation (H2, CO2, CH4) → bloating, flatulence, cramps
- Severity is dose-dependent - small amounts often tolerated
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