Obstetrics & gynaecology · UKMLA & AKT

Menopause

A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise menopause — the full SA Note notes add investigations, management, complications and 10 practice questions.

Key high-yield points

  • Premature ovarian insufficiency (POI) = loss of normal ovarian function before age 40, affecting ~1 in 100 women
  • Hormonal signature: FSH >40 IU/L on two occasions at least 4-6 weeks apart + oestradiol <100 pmol/L
  • Always exclude: pregnancy, hypothyroidism (TSH), hyperprolactinaemia (prolactin) in secondary amenorrhoea

Menopause over 45 is a clinical diagnosis - bloods not routinely needed. Investigate when symptoms occur under 45 or diagnosis is unclear.

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