Obstetrics & gynaecology · UKMLA & AKT

Menopause

A free high-yield preview for the UKMLA Applied Knowledge Test, covering how to recognise this condition. The full SA Note notes add investigations, management and complications, with practice questions on this topic.

Key high-yield points

  • Premature ovarian insufficiency (POI) = loss of normal ovarian function before age 40, affecting ~1 in 100 women
  • Hormonal signature: FSH >40 IU/L on two occasions at least 4-6 weeks apart + oestradiol <100 pmol/L
  • Always exclude: pregnancy, hypothyroidism (TSH), hyperprolactinaemia (prolactin) in secondary amenorrhoea

Menopause over 45 is a clinical diagnosis - bloods not routinely needed. Investigate when symptoms occur under 45 or diagnosis is unclear.

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