Mental health · UKMLA & AKT
Mixed dementia
A free high-yield preview for the UKMLA Applied Knowledge Test, covering how to recognise this condition. The full SA Note notes add investigations, management and complications, with practice questions on this topic.
Key high-yield points
- Simultaneous presence of Alzheimer's disease (AD) pathology AND cerebrovascular disease - accounts for ~10-20% of all dementia cases (likely underestimate as often only confirmed post-mortem)
- AD and vascular pathology are synergistic, not additive - amyloid impairs cerebrovascular autoregulation; ischaemia lowers threshold for amyloid to become clinically manifest → more rapid decline than either alone
Unlock the full Mixed dementia revision
Get the complete high-yield notes (4 more sections covering investigations, management and complications), practice questions, mock exams and Sal, the AI tutor. Start free.