Mental health · UKMLA & AKT

Vascular dementia

A free high-yield preview for the UKMLA Applied Knowledge Test, covering how to recognise this condition. The full SA Note notes add investigations, management and complications, with practice questions on this topic.

Key high-yield points

  • Second most common cause of dementia in the UK (~15-20% of cases) after Alzheimer's disease
  • Caused by cerebrovascular disease (ischaemic or haemorrhagic injury) - white matter predominantly affected (vs cortical grey matter in Alzheimer's)
  • CADASIL - most important genetic cause; *NOTCH3* mutation, autosomal dominant, young-onset VaD with recurrent strokes and migraine with aura

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