Child health · UKMLA & AKT

Neonatal hepatitis and cholestasis

A free high-yield preview for the UKMLA Applied Knowledge Test, covering how to recognise this condition. The full SA Note notes add investigations, management and complications, with practice questions on this topic.

Key high-yield points

  • Conjugated (direct) hyperbilirubinaemia in a neonate is always pathological. The most surgically urgent cause is biliary atresia - progressive fibro-inflammatory obliteration of the extrahepatic bile ducts leading to biliary cirrhosis and liver failure without treatment.

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