Child health · UKMLA & AKT

Neonatal hepatitis and cholestasis

A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise neonatal hepatitis and cholestasis — the full SA Note notes add investigations, management, complications and 10 practice questions.

Key high-yield points

  • Conjugated (direct) hyperbilirubinaemia in a neonate is always pathological. The most surgically urgent cause is biliary atresia - progressive fibro-inflammatory obliteration of the extrahepatic bile ducts leading to biliary cirrhosis and liver failure without treatment.

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