Endocrine & metabolic · UKMLA & AKT

Non-functioning pituitary adenoma

A free high-yield preview for the UKMLA Applied Knowledge Test, covering how to recognise this condition. The full SA Note notes add investigations, management and complications, with practice questions on this topic.

Key high-yield points

  • NFPAs account for ~15% of all pituitary adenomas - most common pituitary macroadenoma presenting to neurosurgery
  • Produce no clinically active hormone - grow silently until large enough to compress surrounding structures
  • Typical presentation age 30-60; usually macroadenomas at diagnosis

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