Endocrine & metabolic · UKMLA & AKT
Cushing's disease
A free high-yield preview for the UKMLA Applied Knowledge Test, covering how to recognise this condition. The full SA Note notes add investigations, management and complications, with practice questions on this topic.
Key high-yield points
Cushing's syndrome = cortisol excess from any cause. Cushing's disease = Cushing's syndrome caused specifically by an ACTH-secreting pituitary adenoma (most common endogenous cause, ~70%). Always exclude exogenous glucocorticoids first.
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