Child health · UKMLA & AKT
Periventricular leukomalacia
A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise periventricular leukomalacia — the full SA Note notes add investigations, management, complications and 10 practice questions.
Key high-yield points
- PVL is hypoxic-ischaemic white matter injury predominantly in preterm infants (<32 weeks), caused by periventricular watershed ischaemia and/or inflammation damaging pre-oligodendrocyte precursor cells, disrupting myelination.
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