Child health · UKMLA & AKT

Systemic juvenile idiopathic arthritis (Still's disease)

A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise systemic juvenile idiopathic arthritis (still's disease) — the full SA Note notes add investigations, management, complications and 10 practice questions.

Key high-yield points

  • Most severe JIA subtype; accounts for 10-15% of all JIA cases
  • Autoinflammatory (innate immune dysregulation via IL-1 and IL-6), not classic autoimmune - RF and ANA typically negative
  • Peak onset 1-5 years; equal sex distribution

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