Clinical haematology · UKMLA & AKT
yeloproliferative disorders
A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise yeloproliferative disorders — the full SA Note notes add investigations, management, complications and 10 practice questions.
Key high-yield points
- Myeloproliferative neoplasms (MPNs) are clonal HSC disorders causing overproduction of mature myeloid cells. Key division: BCR-ABL1-positive (CML) vs BCR-ABL1-negative (PV, ET, PMF) - driven by JAK2 V617F in ~95% PV, ~60% ET/PMF.
Unlock the full yeloproliferative disorders revision
Get the complete high-yield notes (6 more sections covering investigations, management and complications), 10 practice questions, mock exams and AI tutoring. Start free.