Gastroenterology · UKMLA & AKT

Chronic liver failure and decompensated cirrhosis

A free high-yield preview for the UKMLA Applied Knowledge Test, covering how to recognise this condition. The full SA Note notes add investigations, management and complications, with practice questions on this topic.

Key high-yield points

  • Decompensation defined by: ascites, variceal haemorrhage, hepatic encephalopathy, or jaundice
  • Compensated cirrhosis: median survival ~12 years; decompensated: median survival ~2 years (50% 2-year mortality)
  • UK dominant causes: alcohol-related liver disease (ARLD) and MASLD (formerly NAFLD)

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