Infection · UKMLA & AKT
Clostridioides difficile infection
A free high-yield preview for the UKMLA Applied Knowledge Test, covering how to recognise this condition. The full SA Note notes add investigations, management and complications, with practice questions on this topic.
Key high-yield points
- Gram-positive, anaerobic, spore-forming bacillus - colonises large bowel when normal microbiome is disrupted by antibiotics
- Spores resist alcohol-based hand gel, heat, and acid - survive on surfaces for months
- Toxin A (enterotoxin) - fluid secretion and mucosal inflammation; Toxin B (cytotoxin) - colonocyte death and mucosal ulceration
Unlock the full Clostridioides difficile infection revision
Get the complete high-yield notes (6 more sections covering investigations, management and complications), practice questions, mock exams and Sal, the AI tutor. Start free.