Clinical haematology · UKMLA & AKT

Heparin-induced thrombocytopenia (HIT)

A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise heparin-induced thrombocytopenia (hit) — the full SA Note notes add investigations, management, complications and 10 practice questions.

Key high-yield points

  • HIT is an immune-mediated complication of heparin in which IgG antibodies against PF4-heparin complexes cause paradoxical thrombosis despite a falling platelet count. The dominant risk is thrombosis, not haemorrhage.

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