Acute & emergency · UKMLA & AKT

Metabolic acidosis

A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise metabolic acidosis — the full SA Note notes add investigations, management, complications and 10 practice questions.

Key high-yield points

  • Metabolic acidosis: pH <7.35 + low HCO3- (<22 mmol/L)
  • Respiratory compensation: low pCO2 (hyperventilation/Kussmaul breathing)
  • Partial compensation = pCO2 low but pH still <7.35

Kussmaul breathing is slow, DEEP and laboured - it is the depth, not the rate, that is the hallmark. Classic in DKA and severe metabolic acidosis.

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