Respiratory · UKMLA & AKT
Tuberculosis
A free high-yield preview for the UKMLA Applied Knowledge Test, covering how to recognise this condition. The full SA Note notes add investigations, management and complications, with practice questions on this topic.
Key high-yield points
- Caused by Mycobacterium tuberculosis - aerobic, slow-growing, acid-fast bacillus (AFB)
- Transmission via inhalation of respiratory droplets from active pulmonary TB
- Only 5-10% of immunocompetent individuals with latent TB progress to active disease
- Upper lobes predisposed to reactivation - higher oxygen tension supports aerobic growth
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