Respiratory · UKMLA & AKT
Tuberculosis
A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise tuberculosis — the full SA Note notes add investigations, management, complications and 10 practice questions.
Key high-yield points
- Caused by Mycobacterium tuberculosis - aerobic, slow-growing, acid-fast bacillus (AFB)
- Transmission via inhalation of respiratory droplets from active pulmonary TB
- Only 5-10% of immunocompetent individuals with latent TB progress to active disease
- Upper lobes predisposed to reactivation - higher oxygen tension supports aerobic growth
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