Endocrine & metabolic · UKMLA & AKT
Addison's disease
A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise addison's disease — the full SA Note notes add investigations, management, complications and 10 practice questions.
Key high-yield points
- Primary adrenal insufficiency caused by destruction of the adrenal cortex, impairing cortisol, aldosterone, and adrenal androgen synthesis. Most common cause in the UK is autoimmune adrenalitis (~70-80%), associated with 21-hydroxylase antibodies.
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