Endocrine & metabolic · UKMLA & AKT

Cushing syndrome

A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise cushing syndrome — the full SA Note notes add investigations, management, complications and 10 practice questions.

Key high-yield points

  • Cushing's syndrome - any cause of excess glucocorticoids (broad clinical syndrome)
  • Cushing's disease - specifically ACTH-secreting pituitary adenoma
  • Exogenous (iatrogenic) - most common cause overall; suppresses HPA axis → low/undetectable ACTH

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