Gastroenterology · UKMLA & AKT
Folate deficiency
A free high-yield preview for the UKMLA Applied Knowledge Test. Below are the key points to recognise folate deficiency — the full SA Note notes add investigations, management, complications and 10 practice questions.
Key high-yield points
- Absorbed in the jejunum - destroyed by cooking; found in green leafy vegetables, liver, legumes
- Body stores last only ~4 months (vs 3-5 years for B12) - deficiency develops rapidly
- Essential for DNA synthesis - deficiency impairs nuclear maturation in rapidly dividing cells → megaloblastic anaemia
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