Gastroenterology · UKMLA & AKT
Folate deficiency
A free high-yield preview for the UKMLA Applied Knowledge Test, covering how to recognise this condition. The full SA Note notes add investigations, management and complications, with practice questions on this topic.
Key high-yield points
- Absorbed in the jejunum - destroyed by cooking; found in green leafy vegetables, liver, legumes
- Body stores last only ~4 months (vs 3-5 years for B12) - deficiency develops rapidly
- Essential for DNA synthesis - deficiency impairs nuclear maturation in rapidly dividing cells → megaloblastic anaemia
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